Isopropyl Alcohol - Your Best Defense Against The Pandemic
Isopropyl Alcohol - Your Best Defense Against The Pandemic
The whole world seems to be in turmoil amid the coronavirus pandemic and to be true the overall role of hygiene and alcohol-based hand sanitizers are inevitable in the control of the spreading of the virus- especially in healthcare institutions or in public settings. Over the last few months, there has been an immense surge in the demand for alcohol-based sanitizer products leading to a shortfall in their supply. In addition to these points, this global pandemic is expected to continue therefore these isopropyl-based hand sanitizers will be in demand for a long time to come. In this article, we would be focusing on the importance of isopropyl alcohol and how it can be termed as the best defense against the coronavirus pandemic.
Isopropyl Alcohol-Based Sanitizers As A First Line Measure For Covid-19
In general, isopropyl based hand sanitizers is often considered the cornerstone of COVID-19 prevention and it is indeed essential to reduce the transmission of infection and the colonization of the virus across society and in between health care workers. According to the officials of the World Health Organization, “An alcohol-based sanitizer preparation (i.e. gel, foam or liquid) is designed to be applied on the hands to make all the microorganisms inactive and temporarily suspend their growth. These alcohol-based preparations might be having one or more types of alcohol content and other sorts of active ingredients with humectants and excipients.” Another very important factor that helps in determining the overall efficiency of a hand sanitizer is its alcoholic content. Remember seventy percent of IPA-based hand sanitizers are recommended by the health organizations all across the globe.
Quantification Of IPA in Alcohol-Based Hand Sanitizers
According to the World Health Organization, two different formulations are mainly approved for the compounding. The formulation is based on Isopropyl alcohol (75% v/v) Hydrogen Peroxide (0.125% v/v), Glycerol (1.45 % v/v) and distilled or sterile water. A very important factor that must be considered in the compounding of this type is the content of the alcohol. However, the above formulation has been established to be the most effective against most of the germs and viruses. Adding to all these, it has also been determined that most of the hand sanitizers with less than sixty percent of alcohol content isn’t effective and can leave the consumer at a higher infection risk.
Importance Of Isopropyl Alcohol In Hand Sanitizers
Out of the different variants of hand sanitizers, isopropyl based hand sanitizers are often much more effective in killing viruses and bacteria’s present on the human skin. It can readily act in much less than fifteen to thirty seconds and it can effectively eliminate the pathogens, thereby protecting from several contagious viruses.
Remember viruses are of different sizes and shapes and in most cases, they are embossed in a typical protein coat called the capsid. However, in some virus stains, it is noticed that the capsid comes surrounded by an envelope made of lipid layer. These viruses are often termed as enveloped virus. The IPA present in hand sanitizers assists in fighting with these viruses by dissolving the lipid and by denaturing the proteins. They are known to provide effective protection against many disease-causing micro-organisms. It is also noticed that these pathogens are very much vulnerable at seventy percent alcohol content. So, next time you buy isopropyl alcohol, don’t forget to check the label in order to find out the exact IPA concentration and always look for those hand rubs where the IPA concentration is at least seventy percent or above.
Why Seventy Percent IPA Is The Most Effective IPA Concentration For Disinfection
IPA or rubbing alcohol, especially in solutions between sixty and ninety percent of alcohol content is rapidly antimicrobial, especially against viruses, fungi, and bacteria. Once the alcohol concentration drops below fifty percent, their usefulness for disinfection drops rapidly. Remember higher alcohol concentrations do not generate more virucidal, fungicidal, or bactericidal properties. The presence of water content is a very crucial factor especially for inhibiting or destroying the overall growth of different pathogenic microorganisms with the help of IPA.
Here, in this case, water acts as a proper catalyst and plays a very important role in denaturing the protein contents of most vegetative cells. Seventy percent isopropyl alcohol solutions help in penetrating the cell wall better while permeating the entire cell and coagulating all the protein structures. The water content in the concentration, slows down the evaporation process, thereby increasing the contact time while enhancing the overall effectiveness.
Rubbing alcohol concentration which is over ninety-one percent coagulates protein structure immediately as a result of which a protective structure is created, thereby protecting other proteins from further coagulation.
IPA solution greater than ninety-one percent surely helps in killing bacteria but sometimes it requires a much more contact time in order to disinfect. In an analysis, it was recorded that IPA concentration with more than fifty percent of alcohol solution helps in killing Staphylococcus Aureus in just ten seconds, whereas ninety percent of IPA solution with contact time more than two hours is ineffective.
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